Bladder wrack extract is rich in iodine and has been used as a natural supplement for thyroid disorder and for obesity. It has been shown to lower plasma cholesterol levels by competitive inhibition via fucosterols. As cholesterol is a precursor for the biosynthesis of steroid hormones, a reduction in cholesterol bioavailability may lower circulating estradiol levels thereby altering menstrual cycling patterns ⁽¹⁾. An extract of bladder wrack reduced 17,beta-estradiol levels and also acted as a competitive inhibitor of estradiol binding to alpha- and beta- estrogen receptors in vitro ⁽³⁾. In rats, treatment with bladder wrack lengthened overall estrous cycles and reduced circulating 17,beta-estradiol levels ⁽⁴⁾.

Bladder wrack and related seaweed species have been shown to exhibit anti-hypertensive effects via angiotensin-I-converting enzyme inhibition. The antibacterial and antioxidant properties are thought to be due to its polyphenolic contents ⁽¹⁾. Topical bladder wrack extract reduced skin thickness and improved the mechanical/elastic properties ⁽²⁾.

A bladder wrack extract inhibited the cell cyle of proliferating pancreatic cancer cells due to the up-regulation of cell cycle inhibitors, independent of caspases. Also, it showed low cytotoxic activity against non-malignant resting T cells and erythrocytes. Accelerated killing was observed in combination with inhibitors of autophagy ⁽¹¹⁾.