Burdock

Burdock

Burdock

Common Names

  • Lappa
  • wild gobo
  • happy major
  • niubang

For Patients & Caregivers

There is no evidence to support use of burdock to treat cancer, infections, diabetes, or other medical conditions.

Certain components of burdock were shown to stop the growth of bacteria and fungi in lab studies. In animal experiments, the root extract lowered blood sugar, stimulated uterine contractions, induced an immune response, and protected against DNA mutations. However, none of these effects have been shown to occur in the human body.

  • To treat cancer
    There is no scientific evidence to support this use.
  • To lower blood sugar in diabetes
    One small study found that burdock reduced proteinuria and improved post-meal blood glucose levels and lipid metabolism in patients with diabetic nephropathy.
  • To treat eczema and psoriasis
    No scientific evidence supports this use.
  • To treat HIV and AIDS
    This claim is not backed by scientific data.
  • To treat microbial infections
    Although certain compounds in burdock can stop the growth of bacteria and fungi in lab studies, human data are lacking.
  • To promote urination
    No scientific evidence supports this use.
  • To reduce wrinkles
    One clinical study found that application of a cream containing burdock extract improved the appearance of wrinkled skin. However, more studies are needed to confirm this effect.
  • Some burdock teas are contaminated with alkaloids such as atropine from the belladonna plant, which can cause undesirable effects on the nervous system.
  • You are pregnant (Burdock may stimulate the uterus and increase the risk of premature delivery).
  • You are taking hypoglycemic medication for diabetes (Based on animal studies, large doses of burdock may lower blood sugar even further.)
  • Allergic Contact Dermatitis
  • Case Report: A 53-year-old man developed anaphylaxis (redness over his entire body and dyspnea) one hour after taking boiled burdock. His symptoms resolved following treatment.

Burdock is one of the ingredients in the herbal tea Essiac.

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For Healthcare Professionals

Arctium lappa, Arctium majus

Burdock, a perennial plant native to Europe and Northern Asia, is now found worldwide. The root has been consumed as food in Asia for many centuries. The fruit is valued in traditional Chinese medicine as a blood purifier, as a cure for sore throat and colds, and as a topical remedy for skin disorders including acne, eczema and psoriasis. It is also used to treat anorexia, gout, cancer and HIV, although no published clinical studies have evaluated these claims.

Preclinical data indicate that burdock has anti-inflammatory (1), antibacterial (11), antiulcerogenic (12), hepatoprotective (6), antidiabetic (13) and anticancer (14) effects.
A clinical study found that topical application of a formulation containing burdock extract significantly improved dermal extracellular matrix metabolism and visibly reduced wrinkles (4). A mixture of burdock fruit and astragalus root reduced urinary protein and albumin, and improved lipid metabolism and post-prandial blood glucose in patients with diabetic nephropathy (5).

A preparation of burdock tea was found contaminated with atropine, an alkaloid (7). Patients should be aware that poor quality control is a major concern with commercial herbal products.

  • Anorexia
  • Arthritis
  • Cancer treatment
  • Diabetes
  • Eczema
  • HIV and AIDS
  • Microbial infections
  • Promote urination
  • Psoriasis
  • Wrinkle reduction

Arctiin and arctigenin, the lignans present in burdock, exert anti-inflammatory effects by inhibit the pro-inflammatory factors, nitric oxide (NO), tumor necrosis factor-alpha (TNF-a), and interleukin-6 (IL-6) (3) (4). The polyacetylenes and chlorogenic acid have antibacterial properties and are thought responsible for burdock’s beneficial effects against infections and skin disorders (11).


Animal studies indicate that burdock extract induces hypoglycemia and increases carbohydrate tolerance, stimulates uterine smooth muscle, and has antimutagenic activity. The tannin extract induces macrophage response (8). Burdock also exhibits hepatoprotective effects in rats due to its antioxidative activity (6).

Patients allergic to chrysanthemums may exhibit cross-sensitivity to burdock.
Burdock may cause uterine stimulation and should be avoided by pregnant women.

  • Allergic Contact Dermatitis (9)
  • Case Report: A 53-year-old man developed anaphylaxis (redness over his entire body and dyspnea) one hour after consuming boiled burdock. His symptoms resolved following treatment (10).

Hypoglycemics: Theoretically, large doses of burdock may have an additive effect.


  1. Foster S, et al. Tyler’s Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. New York: Hawthorn Herbal Press; 1999.

  2. Knott A, Reuschlein K, Mielke H, et al. Natural Arctium lappa fruit extract improves the clinical signs of aging skin. J Cosmet Dermatol. 2008 Dec;7(4):281-9.

  3. Wang HY, Chen YP. Clinical observation on treatment of diabetic nephropathy with compound fructus arctii mixture. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Jul;24(7):589-92.

  4. Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995 Aug;33(2):134-5.

  5. Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol. 2003 Jun;42(6):472-3.

  6. Chan YS, Cheng LN, Wu JH, et al.  A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011 Oct;19(5):245-54.

  7. Lu LC, Zhou W, Li ZH, et al. Effects of arctiin on streptozotocin-induced diabetic retinopathy in Sprague-Dawley rats. Planta Med. 2012 Aug;78(12):1317-23.

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