- Lipoic acid-palladium complex
- Palladium-alpha-lipoic acid complex
For Patients & Caregivers
Tell your healthcare providers about any dietary supplements you’re taking, such as herbs, vitamins, minerals, and natural or home remedies. This will help them manage your care and keep you safe.
How It Works
Polydox (PolyMVA) has not been shown to treat or prevent any medical condition.
Polydox is a product that contains lipoic acid, acetylcysteine, palladium, B vitamins, and other ingredients. The inventor and promoters of Polydox make many claims for this product that are not supported by any scientific evidence. Some of the components of Polydox are antioxidants (alpha-lipoic acid and acetylcysteine).
For Healthcare Professionals
Polydox is a synthetic product containing lipoic acid-palladium complex (LAPd) and B complex vitamins. Some have attempted to use it to treat cancer, HIV/AIDS, chronic fatigue, psoriasis, and other degenerative disorders. Although animal studies suggest neuroprotective (3), radioproctective (4), antidiabetic (7), and antioxidant (5) (6) properties, Polydox has not been evaluated in clinical trials.
Mechanism of Action
The inventor of Polydox claims that it is a metalo-vitamin with antioxidant activity capable of repairing damaged genes. Polydox is said to have DNA reductase and electroactive properties that alter electron flow in cancer cells at the mitochondrial level, resulting in cytotoxicity.
The manufacturer reports benefits for cancer patients such as increases in energy and appetite, and reduction in cancer-related pain (1) (2). However, no independent scientific data support these claims.
Studies in rats show palladium-alpha-lipoic acid complex protects against aging of myocardium by enhancing the Krebs cycle dehydrogenases and mitochondrial electron transport chain complexes (5). It may increase glutathione levels and reduce lipid peroxidation (6) (7). Animal studies also suggest it may protect against radiation-induced cellular damage (4).