Research Training

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Dr. Jessica Wilcox, MD (Chief Fellow, Class of 2021), and her mentor Dr. Adrienne Boire, MD PhD, discussing their first-in-human clinical trial in development for patients with leptomeningeal metastases.

Dr. Jessica Wilcox, MD (Chief Fellow, Class of 2021), and her mentor Dr. Adrienne Boire, MD PhD, discussing their first-in-human clinical trial in development for patients with leptomeningeal metastases.

Our fellows receive training in clinical research methodology through the NIH-funded Clinical Research and Methodology Curriculum (CRMC). Fellows are also encouraged to participate in longitudinal Protocol Writing and Biostatistics courses.

Throughout training, fellows serve as departmental protocol reviewers—gaining experience in the critical thinking skills required for investigator-initiated study design. They have the opportunity to pair with a faculty mentor to execute a longitudinal basic, translational, or clinical research project.

MSK offers access to some of the top clinical investigators in the field of neuro-oncology. Our fellowship also has a strong track record of producing translational and bench research scientists at the world-renowned MSKC research laboratories. Applicants interested in pursuing bench research are encouraged to contact Alexis Schmidt (Schmida1@mskcc.org) for more information.

Approximately 20 weeks of elective time may be dedicated to research in the first year of fellowship, with an additional 40 weeks in the second year of the fellowship.

Additional Information

Our fellows are given the opportunity to attend and present at national meetings such as the Society for Neuro-Oncology, American Academy of Neurology, American Society of Clinical Oncology, and American Society of Hematology. Participation at these meetings is strongly encouraged. Examples of fellow presentations are below.

Our fellows are supported by intramural funding sources, but as part of the training process they are provided with the tools necessary to apply for extramural sources of funding to support their career development. Those interested in pursuing funding for a basic or translational science project may apply for a two-year K12 training grant.

Recent Presentations in National Meetings

Abstract Title: “Leptomeningeal disease in patients with histone-mutant gliomas”
Presenter: Maria Diaz Ordonez, MD
Mentor: Elena Pentsova, MD
Society of Neuro-Oncology 2021 Meeting


Abstract Title: “Long-term survival and cognitive function follow up of primary CNS lymphoma treated with R-MVP followed by high dose chemotherapy with autologous stem cell transplant consolidation”
Presenter: Kate Therkelsen, MD
Mentor: Christian Grommes, MD
Society of Neuro-Oncology 2021 Meeting


Abstract Title: “The CDK4/6 Inhibitor Abemaciclib in Patients with Recurrent Meningioma and other Primary CNS Tumors”
Presenter: Elizabeth Coffee, MD
Mentor: Thomas Kaley, MD
Society of Neuro-Oncology 2021 Meeting


Abstract Title: “Cerebrospinal fluid circulating tumor cells are a predictive biomarker for proton craniospinal irradiation for leptomeningeal metastases”
Presenter: Maria Diaz Ordonez, MD
Mentor: Elena Pentsova, MD
American Society of Clinical Oncology 2021 Meeting


Abstract Title: “An inflammatory leptomeningeal signature in cancer patients with neurologic manifestations of COVID-19”
Presenter: Jessica Wilcox, MD
Mentor: Adrienne Boire, MD, PhD
American Association for Cancer Research 2021 Meeting


Abstract Title: “Clinical and Molecular Features of a Prospectively-Sequenced Cohort of Glioblastoma Patients with Inherited Disorders in Mismatch Repair”
Presenter: Kevin Elmore, MD
Mentor: Andrew Lin, MD
America Academy of Neurology 2021 Meeting


Abstract Title: “A Retrospective Analysis of Survival Following Treatment with Bevacizumab in Glioblastoma Patients with Radiographically Confirmed Subependymal or Leptomeningeal Spread of Disease”
Presenter: Shama Farooq, MD
Mentor: Alexandra Miller, MD, PhD
Society of Neuro-Oncology 2020 Meeting


Abstract Title: “Malignant Melanoma in Neurocutaneous Melanocytosis: a Retrospective Case Series (2000-2020)”
Presenter: Kevin Elmore, MD
Mentor: Yasmin Khakoo, MD
Society of Neuro-Oncology 2020 Meeting


Abstract Title: “Salvage Resection of Recurrent Previously Irradiated Brain Metastases: Clinical and Radiographic Outcomes”
Presenter: Jessica Wilcox, MD
Mentor: Nelson Moss, MD
Society of Neuro-Oncology 2020 Meeting


Abstract Title: “Circulating Tumor Cells (CTC) in Cerebrospinal Fluid (CSF) as a Predictor of Survival in CNS Metastases”
Presenter: Maria Diaz Ordonez, MD
Mentor: Elena Pentsova, MD
Society of Neuro-Oncology 2020 Meeting

Recent Fellow Research Awards

Fellow: Elizabeth Coffee, awarded training grant during fellowship
MentorKayvan Keshari, Ingo Mellinghoff
Project Title: Hyperpolarized dehydroascorbate (HP DHA) to quantify oxidative stress and its role in the radioresistance of glioblastoma
Source: The Tow Foundation Postdoctoral Fellowship, Center for Molecular Imaging and Nanotechnology


Fellow: Jessica Wilcoxawarded training grant during fellowship
Mentor: Adrienne Boire
Project Title: Phase 1a/1b Trial to Assess Safety and Bioactivity of Intrathecal Deferoxamine in Patients with Leptomeningeal Metastases from Non-Small Cell Lung Cancer
Source: ASCO 2021 Conquer Cancer Young Investigator Award


Fellow: Ivan Kotchetkov, awarded training grant during fellowship
Mentor: Michel Sadelain
Project Title: Development of ANTXR1 Targeting CAR T cells in Glioblastoma
Source: T32 Training Award, Memorial Sloan Kettering Cancer Center


Fellow: Maya Graham, awarded training grant during fellowship
Mentor: Ingo Mellinghoff
Project Title: Dissecting Epigenomic Reprogramming Mediated by Oncohistones in Pediatric High-Grade Glioma Using Human Cerebral Organoids
Source: T32 Training Award, Memorial Sloan Kettering Cancer Center


Fellow: Rebecca Brown, awarded training grant during fellowship
Mentor: Luis Parada
Project Title: Malignant Conversion of Benign Plexiform Neurofibromas in NF1: Role of a Pre-Cancerous Stem Cell-Like Population
Source: T32 Training Award, Memorial Sloan Kettering Cancer Center

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