Andrew McPherson

Assistant Attending

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Andrew McPherson

Office Phone

646-608-7558

Dr. McPherson is an assistant attending computational oncologist. Dr. McPherson’s research focuses on genomic instability, mutational processes and the evolution of cancer genomes through structural change.  Dr McPherson has a strong interest in single cell technologies.  In collaboration with Dr. Shah, Dr. McPherson has helped bring single cell whole genome sequencing to MSK, providing computational support for the Direct Library Preparation protocol, newly implemented at the Integrated Genomics Operation core facility.  Dr. McPherson’s team also provides operational support for single cell sequencing based projects resulting from collaborations with Drs Shah and Aparicio (University of British Columbia), including projects on fitness modelling in cancer and single cell resolution mutational signatures.  In addition, Dr. McPherson’s team provides support for Dr. Shah’s research projects including SPECTRUM.  Supporting work includes data management, genomic analysis and authoring visualization platforms.

Publications

  1. Zhang AW, McPherson A, et al. Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer. Cell. 2018 Jun 14;173(7):1755-1769.e22. doi: 10.1016/j.cell.2018.03.073. Epub 2018 May 10. PubMed PMID: 29754820.
  2. McPherson AW, et al. ReMixT: clone-specific genomic structure estimation in cancer. Genome Biol. 2017 Jul 27;18(1):140. doi: 10.1186/s13059-017-1267-2. Erratum in: Genome Biol. 2017 Oct 6;18(1):188. PubMed PMID: 28750660; PubMed Central PMCID: PMC5530528.
  3. McPherson A, et al. Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer. Nat Genet. 2016 Jul;48(7):758-67. doi: 10.1038/ng.3573. Epub 2016 May 16. PubMed PMID: 27182968.

To view more publications, visit PubMed