Ruslan Soldatov, PhD

Assistant Attending, Computational Oncologist

Ruslan Soldatov, PhD

Assistant Attending, Computational Oncologist
Ruslan Soldatov

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The Institute for Information Transmission Problems in Moscow, Russia; PhD, Institute for Information Transmission Problems

Dr. Soldatov joined the Computational Oncology Service in 2022 as an Assistant Attending. Dr. Soldatov’s research aims to characterize mechanisms of cell fate decisions that coordinate tissue function and quantify how distortions of these mechanisms shape the course of cancer evolution. He develops computational methods to analyze high-throughput measurements at the single-cell resolution, including multi-omics and lineage data. Dr. Soldatov received a PhD in computational biology from the Institute for Information Transmission Problems, Moscow and trained as a postdoctoral fellow at Harvard Medical School with Dr. Peter Kharchenko. Before joining MSKCC, he was an Instructor in Biomedical Informatics at Harvard Medical School. Dr. Soldatov authored many publications in high-ranking journals.


  1. Faure L, Soldatov R, Kharchenko PV, Adameyko I. scFates: a scalable python package for advanced pseudotime and bifurcation analysis from single-cell data. Bioinformatics. 2023 Jan 1;39(1):btac746. doi: 10.1093/bioinformatics/btac746. PMID: 36394263; PMCID: PMC9805561.
  2. Gao T, Soldatov R, Sarkar H, Kurkiewicz A, Biederstedt E, Loh PR, Kharchenko PV. Haplotype-aware analysis of somatic copy number variations from single-cell transcriptomes. Nat Biotechnol. 2023 Mar;41(3):417-426. doi: 10.1038/s41587-022-01468-y. Epub 2022 Sep 26. PMID: 36163550; PMCID: PMC10289836.
  3. Petukhov V, Xu RJ, Soldatov RA, Cadinu P, Khodosevich K, Moffitt JR, Kharchenko PV. Cell segmentation in imaging-based spatial transcriptomics. Nat Biotechnol. 2022 Mar;40(3):345-354. doi: 10.1038/s41587-021-01044-w. Epub 2021 Oct 14. PMID: 34650268.
  4. Bergen V, Soldatov RA, Kharchenko PV, Theis FJ. RNA velocity-current challenges and future perspectives. Mol Syst Biol. 2021 Aug;17(8):e10282. doi: 10.15252/msb.202110282. PMID: 34435732; PMCID: PMC8388041.
  5. Seplyarskiy VB, Soldatov RA, et al; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Population Genetics Working Group, Gilissen C, Wong WSW, Kharchenko PV, Sunyaev S. Population sequencing data reveal a compendium of mutational processes in the human germ line. Science. 2021 Aug 27;373(6558):1030-1035. doi: 10.1126/science.aba7408. Epub 2021 Aug 12. PMID: 34385354; PMCID: PMC9217108.

View a full listing of Ruslan Soldatov’s journal articles.


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Ruslan Soldatov discloses the following relationships and financial interests:

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