Andriy Derkach, PhD

Assistant Attending Biostatistician
Share
Share
Derkach

Education

University of Toronto, Canada

Current Research Interest 

Dr. Derkach’s methodological research focuses on developing new statistical methods that integrate high dimensional molecular and genetic data to detect associations with disease. He is particularly interested in statistical methodologies for high dimensional mediation analysis. Mediation analysis has become a commonly used tool in epidemiologic studies. Dr. Derkach proposes novel methods that can handle some of the practical complexities of the large, complex datasets used by modern scientists.  His methodological updates to mediation analysis can better handle “big data” and show that the resulting inference can be used to improve risk prediction and discrimination of clinical outcomes. He also collaborates with clinical researchers in the Leukemia Service and the Myeloma Service at Memorial Sloan Kettering to design and analyze prospective and retrospective studies.

Publications

Selected peer-reviewed publications:

  1. Derkach A, Moore SC, Boca SM, Sampson JN. Group testing in mediation analysis. Stat Med. 2020 Aug 15;39(18):2423-2436. doi: 10.1002/sim.8546. Epub 2020 May 4. PMID: 32363646; PMCID: PMC8262108.
  2. Derkach A, Pfeiffer RM, Chen TH, Sampson JN. High dimensional mediation analysis with latent variables. Biometrics. 2019 Sep;75(3):745-756. doi: 10.1111/biom.13053. Epub 2019 May 5. PMID: 30859548
  3. Derkach A, Pfeiffer RM. Subset testing and analysis of multiple phenotypes. Genet Epidemiol. 2019 Jul;43(5):492-505. doi: 10.1002/gepi.22199. Epub 2019 Mar 28. PMID: 30920058.
  4. Derkach A, Lawless JF, Sun L. (2015). Score tests for association under response-dependent sampling designs for expensive covariates. Biometrika, 102(4), 988–994.
  5. Derkach A, Lawless JF, Sun L. Robust and powerful tests for rare variants using Fisher’s method to combine evidence of association from two or more complementary tests. Genet Epidemiol. 2013 Jan;37(1):110-21. doi: 10.1002/gepi.21689. Epub 2012 Oct 2. PMID: 23032573.

Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Andriy Derkach discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2021 through disclosure submission in spring 2022). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


View all disclosures