Research Labs

The Chiosis lab uses a unique chemical biology approach to understand, diagnose, and treat cellular processes associated with chronic molecular stress, with the ultimate goal of developing novel therapeutic options for use in the clinic.

Computational chemist John Chodera uses statistical mechanics, molecular modeling, and automated biophysical experiments to help identify new potential therapeutics and investigate mechanisms of drug resistance in cancer.

The Choi Lab develops new synthetic biology tools to study cell-fate decisions in development.

We leverage large-scale unbiased profiling including genomics, transcriptomics, proteomics to identify candidate oncogenes and proteins that are pathogenetically relevant in lymphoma.

The Farese & Walther lab studies the biology and pathology of cellular lipid metabolism, focusing on lipid/energy storage in lipid droplets and sphingolipid metabolism in lysosomes.

Physician-scientist Karuna Ganesh studies stem cell plasticity in metastasis, therapy resistance and tissue regeneration.

The Greenbaum lab utilizes techniques from statistical physics, information theory, and evolutionary biology to better understand the role of self/non-self discrimination in tumor evolution, model response to immunotherapies, and quantify drivers of virus and cancer evolution.

The Lareau Lab synthesizes computational and experimental genomics methods to study how immune cells in our bodies adapt, expand, differentiate, and evolve over an individual’s lifetime.