Research Labs

Physician-Scientist A. Ari Hakimi, MD studies genetic and metabolic mechanisms of immune response in kidney cancers.

Physician-scientist Alan Hanash studies transplant immunology and immune-mediated mechanisms of tissue damage and regeneration.

Physician-scientist Katharine Hsu studies the biology of human natural killer cells and how they contribute to disease processes.

Physician-scientist Christopher A. Klebanoff studies T cell immunobiology with an emphasis on adoptive T cell immunotherapy for the treatment of solid malignancies.

New roles for Notch signaling in the immune system.

The Minn Lab investigates how cancers evolve under chronic inflammation and persistent immune pressure to acquire resistance to immunotherapies, with the goal of developing innovative therapies to restore anti-tumor immunity.

Our group, the Laboratory of Experimental Cancer Immunogenomics, is a multi-disciplinary team of cancer scientists working at the intersection of genomics, molecular genetics, animal modeling, and biostatistical data sciences.

Physician-scientist Rachel Niec studies how cells and tissues communicate to promote health or drive inflammation and cancer.

The Osorio Lab studies the mechanisms of antibody-mediated immunity, with a focus on myeloid cell reprograming to advance cancer immunotherapies.

Computational biologist Dana Pe’er combines single-cell and spatial profiling technologies with machine learning approaches to address fundamental questions in gene regulation, cellular plasticity and cell-cell communication in the contexts of cancer, immunity and development.