Shen R, Olshen AB, Ladanyi M. (2009) Integrative clustering of multiple genomic data types using a joint latent variable model with application to breast and lung cancer subtype analysis. Bioinformatics. 25:2906-12. *The iCluster method we developed was used in a landmark study to discover novel integrated subtypes of breast cancer (Curtis et al., Nature, 2012, 486:346-52).
Shen R, Wang S, Mo Q. (2012) Sparse integrative clustering of multiple omics data sets. Annals of Applied Statistics. 7:269-294.
Hammerman PS, Hayes DN, Wilkerson MD, Schultz N, Bose R, Chu A, Collisson EA, Cope L, Creighton CJ, Getz G, Herman JG, Johnson BE, Kucherlapati R, Ladanyi M, Maher CA, Robertson G, Sander C, Shen R, Sinha R, Sivachenko A, Thomas RK, Travis WD, Tsao MS, Weinstein JN, Wigle DA, Baylin SB, Govindan R, Meyerson M. (2012) Comprehensive genomic characterization of squamous cell lung cancers. Cancer Genome Atlas Research Network. Nature. 27:519-25 *We contributed to the integrated classification of squamous cell lung cancers using multidimensional data.
Mo Q, Wang S, Seshan VE, Olshen AB, Schultz N, Sander C, Powers RS, Ladanyi M, and Shen R*. (2013) Pattern discovery and cancer gene identification in integrated cancer genomic data. Proceedings of the National Academy of Sciences. 12:4245-4250 *Corresponding author