It is used in traditional medicine to treat fatigue, anemia, loss of appetite, dry or scaly skin, night sweating, dryness of mouth, and cancer. Laboratory studies suggest that shi quan da bu tang can help prevent cancer and metastases.
Studies in mice suggest that shi quan da bu tang has anticancer and antimetastatic effects.
A small study of cancer patients showed that it improves survival.
This formula is traditionally used for fatigue. However, scientific evidence is lacking.
There are no clinical data to support this use.
No studies have been conducted to investigate this use.
Dryness of mouth
This use is not backed by clinical data.
There are no scientific evidence to support this use.
Do Not Take If
You have hypersensitivity to any of the components.
You are a breast cancer patient: Dong quai and ginseng present in shi quan da bu tang may stimulate the growth of breast cancer cells.
Shi quan da bu tang is an herbal formula that consists of 10 herbs: Panax ginseng (Ginseng), Angelica sinensis (Dong quai), Paeonia lactiflora (Peony), Atractylodes macrocephala (Atractylodes), Poria cocos (Hoelen), Cinnamomum cassia (Cinnamon), Astragalus membranaceus (Astragalus), Liqusticum wallichii (Cnidium), Glycyrrhiza uralensis (Licorice), and Rehmannia glutinosa (Rehmannia) (1). Also known as Juzen-taiho-to in Japan, it is used in traditional medicine to alleviate symptoms of fatigue, anemia, appetite loss, dry or scaly skin, night sweating, dryness of mouth, and for cancer treatment.
Supporters believe that the beneficial effects of shi quan da bu tang are due to interactions between its components. Studies done in mice suggest that it has antitumor and antimetastatic effects (2)(3)(4)(5)(6)(12) and protects against Alzheimer’s disease (13).
Shi quan da bu tang exhibits radioprotective effects in mice exposed to radiation (7) and protects against myelosuppression induced by anticancer drugs (17). Researchers in Japan administered Shi quan da bu tang to patients with advanced lung cancer for one year and observed an increase in survival time (8). It also alleviated hematotoxicity in patients with breast carcinoma receiving chemotherapy (18). Improvement in anemia has been reported in some studies (14)(15)(16).
No adverse effects have been reported with use of Shi quan da bu tang. However, some components are known to cause interactions with other drugs.
Dryness of mouth
Mechanism of Action
Studies performed in mice suggest that shi quan da bu tang has antitumor and antimetastatic effects (2)(3)(4)(6). These effects are mediated by stimulation of macrophages and natural killer cells. It also exhibits radioprotective effect in mice evidenced by an increase in spleen colony forming unit in mice exposed to radiation (7). In vitro studies using human bone marrow cells indicate that shi quan da bu tang can stimulate hemopoiesis (9).
Breast cancer patients should use this product with caution as dong quai and ginseng may stimulate the growth of breast cancer cells (11).
Tamoxifen: Dong quai has estrogenic activity and may antagonize the effects of tamoxifen used to treat breast cancer. Immunosuppressants: Astragalus may antagonize the effects of immunosuppressants such as tacrolimus and cyclosporine.