Research Labs

Cancer biologist and pediatric oncologist Alex Kentsis leads research in the functional proteomics and molecular pharmacology of refractory childhood cancers.

Mechanisms of genetic and epigenetic cooperativity which drive myeloid transformation; Elucidating and modeling evolution from hematopoietic stem/progenitor cells to clonal hematopoiesis and then to myeloid malignancies; Identification and credentialing novel therapeutic dependencies in myeloid malignancies

Radiochemist Jason Lewis develops molecular imaging agents for the imaging and therapy of cancer.

Dr. Yueming Li studies disease mechanism of Cancer and Alzheimer’s, with the goal of developing novel therapeutics for clinical use.

Physician-scientist Megan Lim studies the molecular pathogenesis of lymphoma.

The Lito lab investigates the properties of oncoproteins that drive cancer cell growth, with a focus on cancers driven by RAS mutations.

Chemical Biologist Minkui Luo develops cutting-edge tools, technologies and concepts to annotate functions of protein-posttranslational modifications and designs inhibitors for cancer therapies.

Joan Massagué studies the control of stem cell growth and phenotype in tumor progression, metastasis, and response to therapy.

Physician-scientist Ingo Mellinghoff studies signal transduction alterations in primary brain tumors.