Research Labs

The Lito lab investigates the properties of oncoproteins that drive cancer cell growth, with a focus on cancers driven by RAS mutations.

The Long laboratory investigates the molecular mechanisms of ion channels and enzymatic membrane proteins and seeks to use these discoveries to benefit humanity.

Chemical Biologist Minkui Luo develops cutting-edge tools, technologies and concepts to annotate functions of protein-posttranslational modifications and designs inhibitors for cancer therapies.

Molecular biologist John Maciejowski studies the causes of complex chromosome rearrangements and the patterns of hypermutation that shape cancer genomes.

New roles for Notch signaling in the immune system.

Kenneth Marians focuses on mechanisms of replication restart and chromosome segregation.

Joan Massagué studies the control of stem cell growth and phenotype in tumor progression, metastasis, and response to therapy.

Molecular and cell biologist Christine Mayr studies how 3′UTRs regulate protein functions and how mRNAs contribute to cytoplasmic organization.

Physician-scientist Babak Mehrara studies the regulation of lymphatic regeneration after surgery and development of lymphedema.