Research Labs

Computational chemist John Chodera uses statistical mechanics, molecular modeling, and automated biophysical experiments to help identify new potential therapeutics and investigate mechanisms of drug resistance in cancer.

Arvin Dar’s lab develops chemical tools and probes to explore disease mechanisms and the structural biology of cancer targets.

The Diver lab studies the physiological roles and molecular mechanisms of understudied membrane-embedded proteins with the goal of revealing novel therapeutic targets for diseases such as pain and cancer.

The Farese & Walther lab studies the biology and pathology of cellular lipid metabolism, focusing on lipid/energy storage in lipid droplets and sphingolipid metabolism in lysosomes.

The Goldberg laboratory focuses on structural and biochemical characterization of intracellular vesicle transport.

The Hite laboratory studies the mechanisms of ion and metabolite transport and the maintenance of genomic integrity.

Immunologist Morgan Huse studies the structure and function of immune cell-cell interactions.

The Lima laboratory studies mechanisms underlying RNA processing as well as post-translational protein modification by ubiquitin-like proteins.

The Long laboratory investigates the molecular mechanisms of ion channels and enzymatic membrane proteins and seeks to use these discoveries to benefit humanity.

The Nikolov laboratory focuses on the structural, biophysical, and biochemical characterization of the molecular mechanisms of cell-cell interactions and signal transduction across the plasma membrane.