Research Labs

We study mutational processes that drive cancer evolution and treatment resistance.

The Lee laboratory studies the mechanisms governing homeostatic turnover and reparative programs in stem cells, with a focus on elucidating how tissue perturbations lead to lung disease.

Computational biologist Christina Leslie focuses on developing machine learning algorithms for computational and systems biology.

Mechanisms of genetic and epigenetic cooperativity which drive myeloid transformation; Elucidating and modeling evolution from hematopoietic stem/progenitor cells to clonal hematopoiesis and then to myeloid malignancies; Identification and credentialing novel therapeutic dependencies in myeloid malignancies

Radiochemist Jason Lewis develops molecular imaging agents for the imaging and therapy of cancer.

Immunologist Ming Li studies mechanisms of immune regulation, and their relevance to diseases including cancer.

Dr. Yueming Li studies disease mechanism of Cancer and Alzheimer’s, with the goal of developing novel therapeutics for clinical use.

Physician-scientist Megan Lim studies the molecular pathogenesis of lymphoma.

The Lima laboratory studies mechanisms underlying RNA processing as well as post-translational protein modification by ubiquitin-like proteins.

The Lito lab investigates the properties of oncoproteins that drive cancer cell growth, with a focus on cancers driven by RAS mutations.