Heeseon An’s lab develops chemical, biological, and proteomics tools to study protein homeostasis of sub-cellular organelles.

The Brown Lab studies how the tissue environment shapes immune cell fate and function during early life immune development, inflammation, and cancer.

Physician-scientist Karuna Ganesh studies stem cell plasticity in metastasis, therapy resistance and tissue regeneration.

Systems biologist Thomas Norman develops new computational and functional genomics approaches for studying how genes interact to realize complex phenotypes.

Physician-scientist Samuel Bakhoum studies the role of chromosomal instability in tumor evolution and metastasis.

The Vierbuchen laboratory directs the differentiation of mouse and human pluripotent stem cells to characterize fundamental mechanisms of neuronal cell fate specification and function.

The Hite laboratory studies the mechanisms of intracellular ion transport.

Cancer biologist Tuomas Tammela investigates cellular heterogeneity in lung, pancreatic and colon cancers.

Yael David’s lab develops and applies methods in chemical biology toward studying epigenetic regulation and its correlation with disease states.

Physician-scientist Piro Lito studies oncoproteins that drive cancer cell growth.

Chemical biologist Daniel Bachovchin designs selective inhibitors to study enzymes and pathways in cancer and immune system signaling.

Molecular geneticist Elli Papaemmanuil performs systematic interrogations of well-annotated clinical trial cohorts in leukemia and cancer to explore how the compound genetic and clonal architecture in patients' leukemias and tumors dictate clinical phenotype, disease progression, and clinical outcomes.